I've spent the last 3 months since I got the Virus TI Snow, on and off, trying to set the Virus up in my DAW and after at first not even being able to install the latest OS, I believe I now have close to the most stable result possible in my DAW. I'll post my setup in case anyone wants to recreate it. It isn't perfect. I'm still trying to get my Native Instruments Maschine to work alongside the Virus (so far opening an instance of both Maschine and Virus Control causes the Virus USB audio to crackle and pop).
AMD HD 5xxx
RME HDSPe AIO
FL Studio 10.0
Now, audio from the Virus still isn't perfect. I get very minor white noise, and it is pretty faint, but I'm convinced it is still due to the USB environment. I have the Virus connected to a USB 2.0 port on the MOBO and every other device connected to two PCI USB expansion cards.
If I can't find a way to connect the Maschine, and perhaps even if I do, I will add optional analog inputs to my RME HDSPe AIO; the product is RME AI4S-192. Then I can bypass/silence/mute the USB audio while still keeping VC for patch tweaking and it should sound amazing