I think many of the issues to do with different sound in VC than in standalone mode are removed if you work at 48khz. I always used to work at 44, but recently thought I'd test the Virus at 48khz and I think it sounds much better. It's annoying in Cubase to switch sample rates, but well worth it - I always thought the virus sounded dead in Cubase, now I run at 48khz it sounds just like it does in standalone mode.
i hope this helps
T Shark