The Virus ti must have the same buffer setting than your soundcard !!!
to find out, just change the asio driver from soundcard to virus ti, AND check the buffersize.
the ti worked with 128 + save buffer. and the motu worked with 512. ( wrong setting)
so i changed the asio driver back to motu interface AND changed the buffersize to 128 !!!
if that all not works, CHECK IN WINDOWS SYSTEM the driver again, sometimes if you connect other mididevices the TI' driver is false.
choose the AUDIO DRIVER 2.8.45 for OS 4.5.3 !!! NOT 2.9.43 !!!! tripple check them always after connecting other usb devices.
if that all not works, disconnect ALL usb devices and firewire devices (mouse and keyboard for writing NOT)
make restart, use a registry cleaner, make restart, connect a belkin usb, make restart, install virus ti, ( connect first usb to belkin, then the powercable)
check after that the driver 2.8.45 for OS 4.5.3. make restart, if all drivers of virus Ti' correct and your pc can find the virus again, disconnect
the TI from Powersupply and install the soundcard driver, restart again, connect your soundcard, install the rest of your soundcard, restart,
connect virus ti, check the driver number again,
turn off the onboard soundcard (realtek on asus boards)
start cubase, and set the buffersize form motu to 128, click ok, change Asio from motu to Virus Ti, set buffer to 128+save buffer, click ok,
change the Asio soundcard from Virus Ti' back to motu.
hope that will help.