Managed to get OS 5 beta to work on my macbook pro 2012 w retina display. OS 4.5.0.3 was not recognized (reinstalled and ran virus control center many times). I went out on a limb and decided to try OS5 beta. After installation, the mac recognized the virus, but I could not get any sound out of the TI plugin. I shutdown, waited a few minutes and tried to open the plugin in Logic Pro 9.1.7 again. This time I got a bunch of glitched out noise. I felt heart broken.
Fast forward a few days... I decided to reproduce/demonstrate the issue to a colleague only to find the plugin loaded up perfectly. All new OS 5 features seem to be working with minimal sync issues (less than on my mac pro PPC running mac os10.5.8).
The glitching noise came back after the system had been idle for a few hours. I shut down the mac, and ran the virus control center app to redetect the virus. Problem solved.
I'm very happy that it's working, and the new OS 5 features are awesome! 