I'm not sure who that comment was directed at "it's more than just some settings". Absolutely it's Apple who have made significant architectural changes - firstly the move to only supporting 64-bit (which is what this thread is about really) - and then the move to user-mode drivers going forward.
However Access have been completely non-comital around whether they are going to update their Mac software or not. That's unacceptable. Some of us would quite happily pay for them to work on an update.
Also I strongly disagree with your comment around the buyers of a new TI hardware being at fault and negligent if they don't research Mac compatibility. Access should be actively highlighting the Mac compatibility issue. If they aren't then it's Access that is negligent and at fault.
The comment was made against the general sentiment going around this thread.
Now the '64bit only' was not the killer, Access has a 64bit application available and works just fine. What killed the Virus in Catalina was the new rule to prohibit kernel extensions. The philosophy that Apple has determined where you as a user cannot determine what a computer can or cannot do within its hardware possibilities is beyond apprehension. The trend from the app store only is being propelled further on their platform and you have to tweak settings to actually be able to install 3rd party plugins, even on Mojave. It's ridiculous. All this to vendor lock you in, and so they can get their 30% piece of the pie from any sales.
Could you as a developer (Access) have foreseen this in the past? Not really. Now the task at hand to make it compatible with the ARM architecture makes it even more complicated than it was before and boy it would mean a full code overhaul. So I'll go on a limb here and guess that Apple knew what was coming and correctly scheduled it on their last intel branch models and quote 'security' as their main reason, taking away scrutiny from the M1 that would have caused the same issues and even on a lower architectural level.
As for my previous statement about Access not being at fault for Integration part, I stand by it. Also they do their due diligence by making sure the information is available on their site and forum that Mac currently has issues. The one part where I do agree with you, is that their transparency in regards to the future and a possible resolve, are sub-par.