Not with the Virus, it was a specialised driver and API that handled MIDI and audio streaming to the unit. The virus was never class compliant
For MIDI, yes a driver is needed. Hence the simple MIDI driver. However, if you use the Aura plugin, that doesn't use a special driver to get audio streaming. All it does, is change the setting in the Virus to allow USB audio.
Without a driver, on the new MacOSes, if you go into audio settings, you'll see the Virus recognised as an audio device with 6 inputs.