I just upgraded my old Virus B to a Virus TI, and have spent the last month taking it through the paces. I absolutely love it (using the last stable OS, not the beta of the new one), and most of the "I wish I could" features just took me figuring out how to do them.
The only thing I would request for a new version would be a master reverb/delay, moreso for the reverb. The Virus reverb sounds fantastic, but it sucks up voices very quickly with complex arrangements, particularly if I have it on more than one part. I've found myself shutting it off for live use (though using it for recording). If there was a master reverb, to which each part could send, it seems that would be more CPU efficient, allowing me to use it more.
Other than that though, brilliant kit!